For chronic ACS, what is the recommended rosuvastatin dosing range?

• A. 5-10 mg daily
• B. 20-40 mg daily
• C. 10-20 mg daily
• D. 40-80 mg daily

Answer: (B)

In chronic ACS, the goal is high-intensity statin therapy to maximize LDL reduction and stabilize plaques. Rosuvastatin at 20–40 mg daily is considered high-intensity and typically lowers LDL by about 50% or more, which has been shown to reduce recurrent cardiovascular events in ACS patients. Dosing below 20 mg is only moderate-intensity and may not achieve the level of risk reduction desired, while doses above 40 mg are not generally recommended due to safety considerations and limited additional benefit. So the recommended rosuvastatin dosing range is 20–40 mg daily.